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Showing posts with label Cervical Smear Test. Show all posts
Showing posts with label Cervical Smear Test. Show all posts

Thursday, 10 May 2012

An 'Ambiguity of Evidence'.

So says Dr. Edward Stefanek with regards to Cancer Screening in an article in Medscape Today. He cites the 'summoning' of women for mammography, contrasting with the 'informed choice' paradigm that exists for men with possible prostrate cancer. He suggests too that this is paternalistic, I would say more likely misogynistic as well, because men are viewed as being participants in some sort of  'club' by simple virtue of their sex, when it comes to honesty in health care. In fact the first rule of misogyny (just like 'fight club') is that we don't talk about misogyny.

Well, I for one don't want to belong to any such club, fraternity or organisation. I do not want to labelled as a feminist either, because I do not wish to 'steal' the term from women. I want to be known as an equal, and one who is just as vulnerable, fallible and more importantly human as is any woman. I am not strident (except in this view) aggressive or demanding of any submission (from women) and feel some men are 'spoiling' it for the rest of us, and the greatest of these are the those who lurk in Medicine, and within that cohort those who continually ram home the message that 'screening saves lives'. Well, patently it does not. It may facilitate an intervention that may do so, but screening per se cannot save any life.

Screening for all cancers is constantly on the rise, despite the fact of the paucity of evidence that exists to support it's continued promotion by the NHS. Medscape also featured Carole Schroeder  who has an interesting blog that provides good information for men about prostrate cancer, but the main thread is that for far too long, women in general (and occasionally men) have been subjected to a constant tirade that they are taking "unacceptable" risks with their health unless they submit to screening. Mammography leads the way despite the fact that recent studies have clearly shown that it is not effective for most and can be catastrophic for some as I detailed in a previous post. There is now a groundswell of opinion rising to ensure that all those who participate are fully informed of the risks, benefits and harms of the process, instead of the current paradigm of inflating the the risks of breast cancer and concealing the harms of mammography. The the BMJ highlighted this last July and I wrote about the innate misogyny displayed in many of the testing regimes, aimed at women, only recently.

A recent development however, is the call for younger women to be 'screened' for cervical cancer, which to be frank is bordering on the dangerous, but when a young Nottingham woman was diagnosed with cervical cancer the pressure was applied both at local and National level for this cohort to be screened. This is despite the fact that only ten deaths from this form of cancer in 20-24 year olds was recorded in the whole of England and Wales in 1988-1989 and it has subsequently 'fallen of a cliff in mortality terms down to 3.7 deaths per 100,000 by the turn of the century (overall mortality). So despite the fact that Natalie Carney did actually have cancer, which is appalling, should we then create a whole new subset of tested women because of one isolated case? Women in this age group often have abnormal cells but it is well known that virtually all of these regress spontaneously without intervention, which is largely why young women are not screened. In fact most screened abnormalities are either benign or regress generally but 'over-diagnosis', just as in mammography, dominates cervical screening. But there is a bigger issue, as always and that is Coercion.

Persuasive tactics predominate all cancer screening testing. The NHS and it's GP's in particular values it out of any proportion to the benefits, but it is a political imperative, maybe to show that they care (sic). 'List and chase' was the tactic employed in the 90's along with 'hit that target', all to encourage GP's to recruit women to the Cytology Screening Programme so they could get their target payments. Yes, they get paid substantial sums for achieving an 80% uptake of testing in the 25 to 64 yr old practise cohort. In fact until payments were commenced uptake was quite low, but once the money was there that all changed. One GP is alleged to have said, "We are afraid of missing our targets, not missing a cancer" (Journal of Medical Ethics 1998;24:151-157). I think that sums up the position quite nicely.

There is little in the way of information provided to women targeted, just exhortations that 'you put your life at risk, by not complying', or ' REMEMBER - regular smears saves lives' and other such coercive statements that are simply not borne out by the evidence. A balanced view is never given and feminine autonomy is usurped by this type of inflammatory rubbish because experts cannot predict the incidence of abnormal smears nor those that will definitely progress to invasive cancers. Quite large numbers of those tested are then subjected interminable waits to find out if there cancer is real and many go on to be treated with surgery or radiation for no useful purpose other than 'being sure'. Those who try to shun the tests are often singled out for bombardment with 'phone calls, text messages and mail shots that are akin to blackmail, foretelling all sorts of dire consequences if they continue to abdicate their responsibility to their partners and families.

Current leaflets explaining the test and likelihood of cervical cancer outrageously inflate the benefits saying that screening is responsible for the drop in the rate of mortality, when it was falling before the testing system got underway and there is no evidence whatsoever that the fall in incidence or mortality was due to screening. Almost 30% of actual cancers occurred in women who had adhered totally to screening guidelines. There were 6231 women diagnosed with cervical cancer between 2007 and 2010, in a population in England of 14.6 million. 44% of those cancers were classed as 'micro-invasive' and were conservatively treated by cone biopsy or loop excision (and of course may not have been true cancers). So that is approximately an incidence of 14.4 per 100,000. Or approximately 8 per 100,000 for those with Stage 1B+ Cancer or worst. At 1 in 3000, you are considerably more likely to to be hit by a meteorite ( I know I didn't believe it, but I did check) so let's get this into some sort of perspective. Of course as you get older the incidence and mortality increases, as will be seen from the graph. That of course is in accord with the aetiology of this cancer which can take many long years to develop. But it still remains quite rare. So does it warrant all the attention, cost and stress to women?
Numbers of deaths and age-specific mortality rates for cervical cancer in the UK
More important however, is the treatment of women as a whole as incapable of making an informed decision about their lives and the ethically unacceptable tactics employed to persuade them to bow to the dubious manipulation of the State. We all are (or should be) autonomous adults and it's completely unethical to attempt to infiltrate any of us with dubious medical opinions, statistics or advice instead of treating us a agents of our own destiny. It is generally women rather than men that are treated in this way and it is generally men who do it. I am ashamed of my gender, especially those called 'Doctor'.

Perhaps the words of Professor Michael Baum, one of my medical hero's may be the best ones to end with. They are here.






Sunday, 22 January 2012

Health Misogyny

Health care in general and the NHS in particular, places far too much reliance upon the notion of prevention and 'early' detection of disease, or rather the 'markers' of what is assumed to be a possible or maybe disease, or condition. This particular trait, and it is redolent of all health care models throughout civilisation, is directed more at women than men.

Perhaps the concept of women being fragile, vulnerable to all sorts of ailments diseases and conditions, that are either particular to, or more predominant in their sex than males, is where this founded. And, of course when this process of labelling all women as potential harbingers of their own doom came to pass, it was men who set about building the edifice of treatments, allocated specifically to the 'fairer' sex, to save them from their 'treacherous' hormone ravaged bodies. And what a crock of s**t, it has all turned out to be.

Mammograms, Cervical Smear Tests, Hormone Replacement Therapy, Vaccines targeted for Cervical Cancer, 'Medicalisation' of Pregnancy, Osteoporosis treatments (mainly for women) and the general consensus that women need 'protecting' from the ravages of their own predisposition to ailments arising from their femininity. Men and some women, are unable to resist the urge to prod, poke and peer into the extremities of women simply to reassure themselves, and vulnerable women, that all is as it 'should be'. A whole industry in Medicine and Health care has sprung from this, including the desire of men, often imposed upon women, to aspire to a stereotype image of the size 10 with big breasts and shapely bottoms. Culminating of course in the Breast Augmentation, Reduction and Botox protocols that has spectacularly 'gone wrong' in the case of the PIP debacle.

I have written at length about Screening for Breast Cancer in the past and  more evidence has comes to light about it's futility for most, and the lie perpetrated that many are 'saved', when in fact the so called cancer found, is not really 'cancer' at all. And it would have likely responded to 'watch and wait protocols' rather than going in with the knife, radiation and chemotherapy. The 'treatment' of Ductal Carcinoma In Situ (DCIS) is redolent of this mindset. Studies conducted also continue to find that mammography seems to increase the incidence of breast cancer than reducing it. The main problem is however that women are treated as pawns, and deprived of the information needed to make an informed decision about whether or not, to submit to this 'testing' (sic) protocol.

Cervical Smear Tests are also 'sold' to women as essential to health and whilst there is little harm invoked by them, when an abnormality is detected the 'system' once more tends to 'overtreat' and frighten women into interventions that can be counter productive. Firstly the incidence of cervical cancers is quite low at 2.4 per 100,000 (European age standardised mortality)  and certainly screening young women (up to 30 years) has been shown to be of little worth. The trend also has been been downwards for the past thirty years (from 7.1). As the mortality rate for Prostrate Cancer is rising and  close to 10x  higher at 23.9 per 100,000 it seems strange that this is not targeted, when Cervical Cancer is. But of course 'overdiagnosis' is really the problem in oncology, especially for treatment protocols directed at women and it continues, without abatement.

We now have the HPV vaccine, targeted (again) at young women to prevent cervical cancer and genital warts yet the vaccine (Gardasil/Cervarix) is only admitted as being effective against two strains of the Virus (types 16 and 18) and there are allegedly thirty strains that are cancer promoting. As the target cohort is 11 to 13 years old females (although now men are now being targeted too!) prior to likely sexual activity and protection is only afforded for ten years at most, it seems perverse to leave them without protection in the years when activity is likely to be elevated, so is it worth it? Even of course if you even think that the vaccine is any good in the first place, which viewing the evidence it seems not, to me. I personally feel that the whole concept of an 'epidemic' of HPV infections is pure hype to sell an unproven vaccine, mainly to women, for their daughters, to swell the coffers of  'Pharma' at a time when the 'blockbuster' drugs are coming off patent. Do young girls need a pretty useless vaccine for a relatively easily treated disease of very low incidence? Make up your own mind, your informed mind. This JAMA editorial may help.

And what of HRT? It was proffered as the panacea for menopausal symptoms and the retention of 'youthful vigour' in women of a certain age and although for many it did precisely that, it exacted a price; breast cancer. Even with short term use, risks of both cardiovascular disease and thromboembolism were also increased tremendously and the ovarian cancer risk increased in the oestrogen only cohorts by some 60% (relative risk). Except for extreme cases, it is used rarely for menopausal symptoms today, but that did not stop 'Pharma' from reaping tremendous profits, from an ill conceived and dangerous drug that is now seen as being counterproductive despite its benefit for the prevention of osteoporosis (but not treatment).

Way back in history we had thalidomide, that was targeted at women to eliminate or ameliorate the problems of 'morning sickness' in pregnancy. As most will know, it wreaked terrible havoc with lasting and appalling effects, but now new information is coming to light about a virtually forgotten drug called Diethylstilboestrol (DES) which seems to cause a rare form of cancer of the vagina and cervix called 'clear cell adenocarcinoma' or CCAC, in the second generation .The Independent on Sunday of today, has highlighted this, but the story has been around for some time with $1.5bn paid out already to victims. Surprisingly, this drug is still used in the UK (but rarely) under the 'Apstil' brand for prostrate cancer and advanced breast cancer in post-menopausal women. (Another crock of s**t?). It was another drug invented for the 'medicalisation' of pregnancy.

It is quite rare in fact for any women to have a home birth. They are taught to fear this in case of complications and the need to ensure their offspring are 'safe'. The truth is in fact that home is a much safer place than hospital, as many of us will know, when we went to hospital for one problem and ended up with many more. The following are some interesting statistics.



Births
(  percent of total )
Perinatal Mortality
( per 1000 births )
1958 1970 1958 1970
Hospital 49 66 50.1 27.8
GP Unit 12 19 20.3 6.1
Home 36 12 19.8 4.3
 ( Statistics resulting from 1958 and 1970 perinatal surveys in Britain. Sources: Sheila Kitzinger, Homebirth and Other Alternatives to Hospital, and Marjorie Tew, Journal of the Royal College of General Practitioners, August 1985.)

Prospective mothers will be told that they are putting their baby 'at risk' if they stay at home for their birth, and I would be the first to advocate that any at risk should be hospitalised, but for healthy women, especially in their second pregnancy, with no known risks, it is cheaper, safer and less traumatic for mother and baby. Yet a whole industry has grown up in the NHS to foster the idea that no other protocol should be countenanced.

Women are continually treated as if to be female is an illness in itself and that your whole life has to be conducted under the microscope of the Health care Profession. Many of the ailments that women are heir to have their risk inflated out of all proportion to reality. many, as I have pointed out are very low; much lower than many that are completely ignored by medicine. We continue along the road of epidemiology and genetics as twin pillars of research but it is a blind alley, especially for women, who have suffered more than men in this construct of blaming their ills upon hedonistic lifestyles, stupidity, and poverty. Most if not all of the breakthroughs in medicine have been due to luck more than insight. Failed aspirations are in fact the predominant factor in Health care, and the 'expert committee' the death knell of common sense.

To treat women as the 'milch cow' of medicine is patronising, condescending and it is without doubt misogyny. Doctors and Clinicians should cease this continual search for things they can 'invent' to fill in their time before their wealth laden retirement. Perhaps they have; children. But that must wait for another day.

By writing this post I could perhaps be accused of the sin I am trying the exemplify. I really hope not.